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課程名稱 |
臨床影像學二
Fundamentals of Medical Imaging(Ⅱ) |
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開課學期 |
110-2 |
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授課對象 |
學程 神經生物與認知科學學程 |
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授課教師 |
湯佩芳 |
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課號 |
PT4038 |
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課程識別碼 |
408 43340 |
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班次 |
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學分 |
1.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期三9(16:30~17:20) |
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上課地點 |
實習教室432 |
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備註 |
與邱銘章、鄭建興、彭信逢、周弘傑、陳雅芳、賴達明、林靜嫻、湯頌君、吳文超合授
限本系所學生(含輔系、雙修生) 且 限學士班四年級以上
總人數上限：45人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
課程概要：
本課程為物理治療學系六年學制學生之必修課程，課程內容為成人與小兒常見神經內外科疾病之神經、血管臨床影像判讀，以養成物理治療核心專業能力。內容主要涵蓋﹕(一)神經發展與神經解剖學概觀;(二)電腦斷層(含電腦斷層灌流)造影、磁振造影、血管攝影、正子攝影、與神經超音波等影像成像原理之介紹;(三)正常與異常影像判讀原則;(四)主要成人與小兒神經內外科疾病(含腦中風、頭部外傷、水腦、腦腫瘤、巴金森氏症、失智症、脊髓損傷、脊髓腫瘤與病變、腦性麻痺、遺傳性腦疾病、腦先天畸形等)之神經、血管臨床影像判讀。
本課程採多元學習方式進行，除授課教師講授相關知識之外，亦包含文獻閱讀、討論、報告、與問題導向學習(PBL)等學習活動，以培養學生專業能力、批判思考、終身學習、和跨領域溝通以及團隊合作能力。 |
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課程目標 |
修習學生在結束本課程後，應能：
1. 瞭解電腦斷層、磁振造影、血管攝影、正子攝影、與神經超音波等之影像原理；
2. 瞭解如何判讀正常之電腦斷層腦與磁振造影腦部與脊髓影像；
3. 瞭解如何判讀血管攝影與神經超音波影像；
4. 瞭解如何判讀主要成人即小兒神經內外科疾病之神經、血管影像；
5. 瞭解神經、血管影像判讀結果與臨床表徵間的關係；
6. 學習應用神經、血管影像資訊於成人神經物理治療及小兒神經物理治療主要臨床疾病類別之臨床決策。 |
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課程要求 |
先修科目: 機能解剖學 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 備註： 需事先與授課老師預約 |
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指定閱讀 |
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參考書目 |
I. Neuroscience textbooks
A. Bear M, Connors B, Paradiso M. Neuroscience: Exploring the Brain, 3 ed. Baltimore: Lippincott Williams & Wilkins. 2016.
B. Purves D, Augustine GJ, Fitzpatrick D, Hall WC, LaMantia A-S, Mooney RD, Platt ML, White LE. (2018) Neuroscience. 6th ed. Sunderland, MA, USA: Sinaur Associates, Inc.
C. Lundy-Ekman L. Neuroscience Fundamentals for Rehabilitation. 5th ed. St. Louis: Saunders Elsevier; 2018
D. https://nba.uth.tmc.edu/neuroscience/index.htm (Neuroanatomy Online)
II. Neuroanatomy textbooks
A. Haines DE. Neuroanatomy: An Atlas of Structures, Sections, and Systems. 9th Ed. Philadelphia: Wolters Kluwer. 2015.
B. Haines DE. Neuroanatomy Atlas in Clinical Context: Structures, Sections, and Systems. 10th Ed. Philadelphia: Wolters Kluwer. 2019.
C. Kiernan JA, Rajakumar N. Barr’s The Human Nervous System: An Anatomical Viewpoint. 10th Ed. Philadelphia: Wolters Kluwer Lippincott Williams & Wilkins, 2014.
D. Mai JK and Paxinos G. The Human Nervous System [E-book]. 3rd Ed. Burlington: Elsevier Science, 2012
E. Mai JK, Paxinos G, Voss T. Atlas of the Human Brain. 3rd Ed. New York: Academic Press. 2008.
F. Martin J. (Ed.) Neuroanatomy: Text and Atlas. [E-book]. 5th ed. McGraw Hill. 2021
G. Vanderah, TW. Nolte’s the Human Brain: An Introduction to Its Functional Anatomy [E-book]. 7th ed. Philadelphia, PA: Elsevier. 2016.
III. Neuroimaging textbooks
A. Agarwal N. and Port J. D. (Eds.) Neuroimaging: Anatomy Meets Function (1st. Ed.) E-book]. Cham, Springer International Publishing. 2018.
B. Cho ZH (Ed.). 7.0 Tesla MRI Brain Atlas: In-vivo atlas with cryomacrotome correlation (2nd Ed.) [E-book]. Berlin, Heidelberg: Springer. 2015.
C. Gillard JH, Waldman AD, and Barker PB. (Eds.). Clinical MR Neuroimaging: Physiological and Functional Techniques (2nd ed). New York: Cambridge University Press. 2010.
D. Naidich TP. Duvernoy's Atlas of the Human Brain Stem and Cerebellum [E-book]: High-field MRI: Surface Anatomy, Internal Structure, Vascularization and 3D Sectional Anatomy. Vienna: Springer Vienna. 2009.
E. Sanelli PC et al. Neuroimaging: the Essentials. Philadelphia: Wolters Kluwer. 2016.
F. Scarobino T, Pollice S (Editors). Imaging spine after treatment: A case-based Atlas. [E-book]. Milan: Springer Milan. 2014
G. Scarobino T, Pollice S, Popolizio T (Editors). High Field Brain MRI: Use in Clinical Practice (2nd Ed.) [E-book]. Cham: Springer International Publishing. 2017.
H. Scott W. Atlas (Editor). Magnetic Resonance Imaging of the Brain and Spine [E-book]. 5th ed. Philadelphia: Lippincott Williams & Wilkins, 2017.
I. 陳煥武編譯(Catherine Westbrook原著)。圖解核磁共振造影學。台北市:合記。2006。
IV. Other readings: to be determined by instructors
A. Basic principles of imaging
1. Goldman LW. Principles of CT and CT technology. J Nucl Med Technol 2007;35:115-128; quiz 129-130.
2. Currie S, Hoggard N, Craven IJ, Hadjivassiliou M, Wilkinson ID. Understanding MRI: basic MR physics for physicians. Postgrad Med J 2013;89:209-223.
3. Townsend DW. Physical principles and technology of clinical PET imaging. Ann Acad Med Singapore 2004;33:133-145.
4. 郭盈昇(Ying-Sheng Kuo)、陳啟仁(Chi-Jen Chen)、王宣惠(Hsuan-Hei Wang)、關婉君(Wan-Chun Kuan)、蔡承坤(Cheng-Kun Tsai)、邱文達(Wen-Ta Chiu)。磁振造影於中樞神經系統之運用(The Applications of MRI in Central Nervous System)。科儀新知; 2011; 180期: P4 - 17。
B. Aging brain
1. Jagust W, D’Esposito M. Imaging the Aging Brain [electronic resource]. Oxford Scholarship Online. 2009.
C. Stroke
1. Campbell BC, Parsons MW. Imaging selection for acute stroke intervention. Int J Stroke 2018;13:554-567.
2. Kamalian S, Lev MH. Stroke Imaging. Radiol Clin North Am 2019;57:717-732.
3. Vilela P, Rowley HA. Brain ischemia: CT and MRI techniques in acute ischemic stroke. Eur J Radiol 2017;96:162-172.
V. Useful on-line learning resources
A. https://learnneuroradiology.com/
B. https://radiologyassistant.nl/neuroradiology/
C. https://radiopaedia.org
D. http://www.med.harvard.edu/aanlib/
E. http://www.mr-tip.com/
F. http://www.mrisafety.com/lectures.asp
G. http://www.thehumanbrain.net/; http://www.thehumanbrain.info/mri/mr-navigator.php
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
平時成績 |
20% |
上課參與(6 %)、提問及討論(6 %)、2/16小考與作業(8 %) |
2. |
課堂報告 |
10% |
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3. |
期中考 |
30% |
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4. |
期末口頭報告 |
20% |
PDF檔請於口頭報告前一天上傳NTU Cool |
5. |
期末書面報告 |
20% |
PDF檔請於口頭報告後一週內上傳NTU Cool |
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週次 |
日期 |
單元主題 |
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第1週 |
2/16 |
Course overview; Quiz on neuroanatomy
Introduction to on-line neuroimage resources (in-class practice) |
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第2週 |
2/23 |
Introduction to medical imaging: CT (non-contrast, contrast, perfusion, angiography), MRI (basic structure, diffusion, susceptibility, angiography, perfusion, and spectroscopy), and PET (PET CT) |
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第3週 |
3/2 |
Use of neuroimaging in neurorehabilitation: Student presentations of readings and discussions (3 groups) |
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第4週 |
3/9 |
General principles of image reading and imaging in cerebrovascular disorders |
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第5週 |
3/16 |
Neuroimaging in acute ischemic stroke |
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第6週 |
3/23 (5:30-6:20 pm) |
Neuroimaging in cerebral hemorrhage, hydrocephalus, traumatic brain injury, and spinal disorders before and after neurosurgery |
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第7週 |
3/30 |
Neuroimaging in white matter lesions, MS, & infection |
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第8週 |
4/6 |
Midterm exam |
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第9週 |
4/13 |
Neuroimaging in brain tumors |
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第10週 |
4/20 |
Neuroimaging in normal aging and dementia |
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第11週 |
4/27 |
Neuroimaging in Parkinson’s disease and other basal ganglia disorders |
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第12週 |
5/4 |
Pediatric neuroimaging |
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第13週 |
5/11 |
Ultrasonic imaging in adult neurological disorders |
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第14週 |
5/18 |
Neonatal brain ultrasonic imaging |
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第15週 |
5/25 |
PBL Final reports (3 groups; 3 case reports of 3 types of neurological patients) |
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第16週 |
6/1 |
PBL Final reports (3 groups; 3 case reports of 3 types of neurological patients) |
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